Phenobarbitone 30mg by Uni-Tiech
Product Description
Generic Name:
Phenobarbitone
Trade Name(s):
Phenobarbitone, Epinil, Lumnial, Phenobarb, Epigard, Epitan, Fenobarb, Emgard, Phenetone, Epinil, G 30, Shenobar, Epikon, Shinosun, Barbee, G-60, Barbinol, Epikon, Gardenal, Gee, Phenobarbitone Sodium Inj.
Why it is prescribed (Indications):
This medication is a barbiturate, prescribed for seizures, and treating sleep disorders. It works by slowing the activity in the brain.
How does it work?
Phenobarbital (previously known as phenobarbitone in the UK) belongs to a group of medicines called barbiturates. It is used to treat epilepsy and works by stabilising electrical activity in the brain.
The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals. These signals must be carefully regulated for the brain and nerves to function properly. When abnormally rapid and repetitive electrical signals are released in the brain, the brain becomes over-stimulated and normal function is disturbed. This can result in fits or seizures.
Phenobarbital prevents epileptic fits by preventing the excessive electrical activity in the brain. It is thought to achieve this by affecting certain neurotransmitters in the brain.
Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. GABA is a neurotransmitter that acts as a natural 'nerve-calming' agent. It helps keep the nerve activity in the brain in balance. Glutamate is a neurotransmitter that acts as a natural 'nerve-exciting' agent. It is released when electrical signals build up in nerve cells and subsequently excites more nerve cells. It is thought to play a key role in causing epileptic seizures.
Phenobarbital increases the activity of GABA and decreases the activity of glutamate in the brain. These actions help stabilise the electrical activity in the brain and prevent epileptic fits.
Phenobarbital is available as tablets, elixir and injection. The injection is used to control repeated fitting, when consciousness is not regained between seizures. This condition is called status epilepticus.
Dosage & When it is to be taken:
Adult- PO- The recommended dose is 30 to 60mg once daily or in divided doses.
IM/IV- The recommended dose is 100 to 200mg.
How it should be taken:
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions:
* Caution should be exercised in patients with history of depression, pain, breathing problems, suicidal tendencies, shock, drug dependency, alcoholism, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may cause dizziness, drowsiness, or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It should not be used in children less than 12 years.
Side Effects:
Central Nervous system - Agitation, confusion, involuntary movements, incoordination, CNS depression, nightmares, nervousness, mental disturbance, hallucinations, sleeplessness, anxiety, drowsiness, and dizziness and thinking abnormality.
Respiratory - Difficulty in breathing or shortness of breath.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Miscellaneous - Headache, injection site reactions, hypersensitivity reactions, fever, liver damage and anemia.
Other Precautions:
* Avoid excess dosage.
When it is not to be taken (Contraindications): Contraindicated in patients with acute intermittent porphyria, severe lung insufficiency, and obstructive sleep apnea, liver and kidney disease.
Generic Name:
Phenobarbitone
Trade Name(s):
Phenobarbitone, Epinil, Lumnial, Phenobarb, Epigard, Epitan, Fenobarb, Emgard, Phenetone, Epinil, G 30, Shenobar, Epikon, Shinosun, Barbee, G-60, Barbinol, Epikon, Gardenal, Gee, Phenobarbitone Sodium Inj.
Why it is prescribed (Indications):
This medication is a barbiturate, prescribed for seizures, and treating sleep disorders. It works by slowing the activity in the brain.
How does it work?
Phenobarbital (previously known as phenobarbitone in the UK) belongs to a group of medicines called barbiturates. It is used to treat epilepsy and works by stabilising electrical activity in the brain.
The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals. These signals must be carefully regulated for the brain and nerves to function properly. When abnormally rapid and repetitive electrical signals are released in the brain, the brain becomes over-stimulated and normal function is disturbed. This can result in fits or seizures.
Phenobarbital prevents epileptic fits by preventing the excessive electrical activity in the brain. It is thought to achieve this by affecting certain neurotransmitters in the brain.
Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. GABA is a neurotransmitter that acts as a natural 'nerve-calming' agent. It helps keep the nerve activity in the brain in balance. Glutamate is a neurotransmitter that acts as a natural 'nerve-exciting' agent. It is released when electrical signals build up in nerve cells and subsequently excites more nerve cells. It is thought to play a key role in causing epileptic seizures.
Phenobarbital increases the activity of GABA and decreases the activity of glutamate in the brain. These actions help stabilise the electrical activity in the brain and prevent epileptic fits.
Phenobarbital is available as tablets, elixir and injection. The injection is used to control repeated fitting, when consciousness is not regained between seizures. This condition is called status epilepticus.
Dosage & When it is to be taken:
Adult- PO- The recommended dose is 30 to 60mg once daily or in divided doses.
IM/IV- The recommended dose is 100 to 200mg.
How it should be taken:
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions:
* Caution should be exercised in patients with history of depression, pain, breathing problems, suicidal tendencies, shock, drug dependency, alcoholism, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may cause dizziness, drowsiness, or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It should not be used in children less than 12 years.
Side Effects:
Central Nervous system - Agitation, confusion, involuntary movements, incoordination, CNS depression, nightmares, nervousness, mental disturbance, hallucinations, sleeplessness, anxiety, drowsiness, and dizziness and thinking abnormality.
Respiratory - Difficulty in breathing or shortness of breath.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Miscellaneous - Headache, injection site reactions, hypersensitivity reactions, fever, liver damage and anemia.
Other Precautions:
* Avoid excess dosage.
When it is not to be taken (Contraindications): Contraindicated in patients with acute intermittent porphyria, severe lung insufficiency, and obstructive sleep apnea, liver and kidney disease.
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