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Monday 30 November 2015

Ciproxin 500mg by Bayer

Ciproxin 500mg by Bayer



Product Description
Generic Name:

 Ciprofloxacin

 WHAT CIPROXIN IS AND WHAT IT IS USED FOR:

Ciproxin is an antibiotic belonging to the fluoroquinolone family. The active substance is ciprofloxacin. Ciprofloxacin works by killing bacteria that cause infections. It only works with specific strains of bacteria.

For Adults:

Ciproxin is used in adults to treat the following bacterial infections:

respiratory tract infections
long lasting or recurring ear or sinus infections
urinary tract infections
infections of the testicles
genital organ infections in women
gastro-intestinal tract infections and intra-abdominal infections
skin and soft tissue infections
bone and joint infections
to treat infections in patients with a very low white blood cell count (neutropenia)
to prevent infections in patients with a very low white blood cell count (neutropenia)
to prevent infections due to the bacterium Neisseria meningitidis
anthrax inhalation exposure
If you have a severe infection or one that is caused by more than one type of bacterium, you may be given additional antibiotic treatment in addition to Ciproxin.

For Children and adolescents:

Ciproxin is used in children and adolescents, under specialist medical supervision, to treat the following bacterial infections:

lung and bronchial infections in children and adolescents suffering from cystic fibrosis
complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis)
anthrax inhalation exposure
Ciproxin may also be used to treat other specific severe infections in children and adolescents when your doctor considered this necessary.

BEFORE YOU TAKE CIPROXIN:
Do not take Ciproxin if you are:
allergic (hypersensitive) to the active substance, to other quinolone drugs or to any of the other ingredients of Ciproxin (see section 6)
taking tizanidine (see Section 2: Taking other medicines)
Take special care with Ciproxin:
Before taking Ciproxin:

Tell your doctor if you:

have ever had kidney problems because your treatment may need to be adjusted
suffer from epilepsy or other neurological conditions
have a history of tendon problems during previous treatment with antibiotics such as Ciproxin
have myasthenia gravis (a type of muscle weakness)
have a history of abnormal heart rhythms (arrythmias)
While taking Ciproxin:

Tell your doctor immediately, if any of the following occurs while taking Ciproxin. Your doctor will decide whether treatment with Ciproxin needs to be stopped.

Severe, sudden allergic reaction (an anaphylactic reaction/shock, angio-oedema). Even with the first dose, there is a small chance that you may experience a severe allergic reaction with the following symptoms: tightness in the chest, feeling dizzy, sick or faint, or experiencing dizziness when standing up. If this happens, stop taking Ciproxin and contact your doctor immediately.
Pain and swelling in the joints and tendinitis may occur occasionally, particularly if you are elderly and are also being treated with corticosteroids. At the first sign of any pain or inflammation stop taking Ciproxin and rest the painful area. Avoid any unnecessary exercise, as this might increase the risk of a tendon rupture.
If you suffer from epilepsy or other neurological conditions such as cerebral ischemia or stroke, you may experience side effects associated with the central nervous system. If this happens, stop taking Ciproxin and contact your doctor immediately.
You may experience psychiatric reactions the first time you take Ciproxin. If you suffer from depression or psychosis, your symptoms may become worse under treatment with Ciproxin. If this happens, stop taking Ciproxin and contact your doctor immediately.
You may experience symptoms of neuropathy such as pain, burning, tingling, numbness and/or weakness. If this happens, stop taking Ciproxin and contact your doctor immediately.
Diarrhoea may develop while you are taking antibiotics, including Ciproxin, or even several weeks after you have stopped taking them. If it becomes severe or persistent or you notice that your stool contains blood or mucus, stop taking Ciproxin immediately, as this can be life-threatening. Do not take medicines that stop or slow down bowel movements and contact your doctor.
Tell the doctor or laboratory staff that you are taking Ciproxin if you have to provide a blood or urine sample.
Ciproxin may cause liver damage. If you notice any symptoms such as loss of appetite, jaundice (yellowing of the skin), dark urine, itching, or tenderness of the stomach, stop taking Ciproxin and contact your doctor immediately.
Ciproxin may cause a reduction in the number of white blood cells and your resistance to infection may be decreased. If you experience an infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore throat/pharynx/mouth or urinary problems you should see your doctor immediately. A blood test will be taken to check possible reduction of white blood cells (agranulocytosis). It is important to inform your doctor about your medicine.
Tell your doctor if you or a member of your family is known to have a deficiency in glucose-6-phosphate dehydrogenase (G6PD), since you may experience a risk of anemia with ciprofloxacin.
Your skin becomes more sensitive to sunlight or ultraviolet (UV) light when taking Ciproxin. Avoid exposure to strong sunlight, or artificial UV light such as sunbeds.
Taking other medicines:
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including any that you obtained without a prescription.

Do not take Ciproxin together with tizanidine, because this may cause side effects such as low blood pressure and sleepiness (see Section 2: "Do not take Ciproxin").

The following medicines are known to interact with Ciproxin in your body. Taking Ciproxin together with these medicines can influence the therapeutic effect of those medicines. It can also increase the probability of experiencing side effects.

Tell your doctor if you are taking:

warfarin or other oral anti-coagulants (to thin the blood)
probenecid (for gout)
methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis)
theophylline (for breathing problems)
tizanidine (for muscle spasticity in multiple sclerosis)
clozapine (an antipsychotic)
ropinirole (for Parkinson’s disease)
phenytoin (for epilepsy)
Ciproxin may increase the levels of the following medicines in your blood:

pentoxifylline (for circulatory disorders)
caffeine
Some medicines reduce the effect of Ciproxin. Tell your doctor if you take or wish to take:

antacids
mineral supplements
sucralfate
a polymeric phosphate binder (e.g. sevelamer)
medicines or supplements containing calcium, magnesium, aluminium or iron
If these preparations are essential, take Ciproxin about two hours before or no sooner than four hours after them.

Taking Ciproxin with food and drink:
Unless you take Ciproxin during meals, do not eat or drink any dairy products (such as milk or yoghurt) or drinks with added calcium when you take the tablets, as they may affect the absorption of the active substance.

Pregnancy and breast-feeding:
It is preferable to avoid the use of Ciproxin during pregnancy. Tell your doctor if you are planning to get pregnant.

Do not take Ciproxin during breast feeding because ciprofloxacin is excreted in breast milk and can be harmful for your child.

Driving and using machines:
Ciproxin may make you feel less alert. Some neurological adverse events can occur. Therefore, make sure you know how you react to Ciproxin before driving a vehicle or operating machinery. If in doubt, talk to your doctor.

HOW TO TAKE CIPROXIN:
Your doctor will explain to you exactly how much Ciproxin you will have to take as well as how often and for how long. This will depend on the type of infection you have and how bad it is.

Tell your doctor if you suffer from kidney problems because your dose may need to be adjusted.

The treatment usually lasts from 5 to 21 days, but may take longer for severe infections. Take the tablets exactly as your doctor has told you. Ask your doctor or pharmacist if you are not sure how many tablets to take and how to take Ciproxin.

Swallow the tablets with plenty of fluid. Do not chew the tablets because they do not taste nice.
Do try to take the tablets at around the same time every day.
You can take the tablets at mealtimes or between meals. Any calcium you take as part of a meal will not seriously affect uptake. However, do not take Ciproxin tablets with dairy products such as milk or
yoghurt or with fortified fruit juices (e.g. calcium-fortified orange juice).
Remember to drink plenty of fluids while you are taking Ciproxin.

If you take more Ciproxin than you should:
If you take more than the prescribed dose, get medical help immediately. If possible, take your tablets or the box with you to show the doctor.
If you forget to take Ciproxin:
Take the normal dose as soon as possible and then continue as prescribed. However, if it is almost time for your next dose, do not take the missed dose and continue as usual. Do not take a double dose to make up for a forgotten dose. Be sure to complete your course of treatment.
If you stop taking Ciproxin:
It is important that you finish the course of treatment even if you begin to feel better after a few days. If you stop taking this medicine too soon, your infection may not be completely cured and the symptoms of the infection may return or get worse. You might also develop resistance to the antibiotic.
POSSIBLE SIDE EFFECTS:

Like all medicines, Ciproxin can cause side effects, although not everybody gets them.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist.

Common side effects:

nausea, diarrhoea
joint pains in children
Uncommon side effects:

fungal superinfections
a high concentration of eosinophils, a type of white blood cell
loss of appetite (anorexia)
hyperactivity or agitation
headache, dizziness, sleeping problems, or taste disorders
vomiting, abdominal pain, digestive problems such as stomach upset (indigestion/heartburn), or wind
increased amounts of certain substances in the blood (transaminases and/or bilirubin)
rash, itching, or hives
joint pain in adults
poor kidney function
pains in your muscles and bones, feeling unwell (asthenia), or fever
increase in blood alkaline phosphatase (a certain substance in the blood)
Rare side effects:

inflammation of the bowel (colitis) linked to antibiotic use (can be fatal in very rare cases) (see Section 2: Take special care with Ciproxin)
changes to the blood count (leukopenia, leukocytosis, neutropenia, anaemia), increased or decreased amounts of a blood clotting factor (thrombocytes)
allergic reaction, swelling (oedema), or rapid swelling of the skin and mucous membranes (angio-oedema)
increased blood sugar (hyperglycaemia)
confusion, disorientation, anxiety reactions, strange dreams, depression, or hallucinations
pins and needles, unusual sensitivity to stimuli of the senses, decreased skin sensitivity, tremors, seizures (see Section 2: Take special care with Ciproxin), or giddiness
eyesight problems
tinnitus, loss of hearing, impaired hearing
rapid heartbeat (tachycardia)
expansion of blood vessels (vasodilation), low blood pressure, or fainting
shortness of breath, including asthmatic symptoms
liver disorders, jaundice (cholestatic icterus), or hepatitis
sensitivity to light (see Section 2: Take special care with Ciproxin)
muscle pain, inflammation of the joints, increased muscle tone, or cramp
kidney failure, blood or crystals in the urine (see Section 2: Take special care with Ciproxin), urinary tract inflammation
fluid retention or excessive sweating
abnormal levels of a clotting factor (prothrombin) or increased levels of the enzyme amylase
Very rare side effects:

a special type of reduced red blood cell count (haemolytic anaemia); a dangerous drop in a type of white blood cells (agranulocytosis ); a drop in the number of red and white blood cells and platelets (pancytopenia), which may be fatal; and bone marrow depression, which may also be fatal (see Section 2: Take special care with Ciproxin)
severe allergic reactions (anaphylactic reaction or anaphylactic shock, which can be fatal - serum sickness) (see Section 2: Take special care with Ciproxin)
mental disturbances (psychotic reactions) (see Section 2: Take special care with Ciproxin)
migraine, disturbed coordination, unsteady walk (gait disturbance), disorder of sense of smell (olfactory disorders), pressure on the brain (intracranial pressure)
visual colour distortions
inflammation of the wall of the blood vessels (vasculitis)
pancreatitis
death of liver cells (liver necrosis) very rarely leading to life-threatening liver failure
small, pin-point bleeding under the skin (petechiae); various skin eruptions or rashes (for example, the potentially fatal Stevens-Johnson syndrome or toxic epidermal necrolysis)
muscle weakness, tendon inflammation, tendon rupture – especially of the large tendon at the back of the ankle (Achilles tendon) (see Section 2: Take special care with Ciproxin)
Frequency not known (cannot be estimated from the available data)

troubles associated with the nervous system such as pain, burning, tingling, numbness and/or weakness in extremities
severe cardiac rhythm abnormalities, irregular heart beat (Torsades de Pointes)
HOW TO STORE CIPROXIN:
Keep out of the reach and sight of children.

Do not use Ciproxin after the expiry date, which is stated on the blister and carton after “EXP”: The expiry date refers to the last day of that month.

This medicinal product does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of any medicines no longer required. These measures will help to protect the environment.

FURTHER INFORMATION:
What Ciproxin contains
The active substance is ciprofloxacin.

Each film-coated tablet contains 500 mg ciprofloxacin (as hydrochloride).

The other ingredients are:

Tablet core:

cellulose microcrystalline, crospovidone, magnesium stearate, maize starch, silica colloidal anhydrous.

Film-coat:

hypromellose, macrogol 4000, titanium dioxide.

Advice/medical education:
Antibiotics are used to cure bacterial infections. They are ineffective against viral infections.

If your doctor has prescribed antibiotics, you need them precisely for your current illness.

Despite antibiotics, some bacteria may survive or grow. This phenomenon is called resistance: some antibiotic treatments become ineffective.

Misuse of antibiotics increases resistance. You may even help bacteria become resistant and therefore delay your cure or decrease antibiotic efficacy if you do not respect appropriate:

dosages
schedules
duration of treatment
Consequently, to preserve the efficacy of this drug:

1 - Use antibiotics only when prescribed.
2 - Strictly follow the prescription.
3 - Do not re-use an antibiotic without medical prescription, even if you want to treat a similar illness.
4 - Never give your antibiotic to another person; maybe it is not adapted to her/his illness.
5 - After completion of treatment, return all unused drugs to your chemist’s shop to ensure they will be disposed of correctly.

Hypnotil 30mg by PHD Pharma

Hypnotil 30mg by PHD Pharma

Product Description
Temazepam:
             
Brand names:
Restoril /Hypnotil

What is temazepam?
Temazepam is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). It affects chemicals in the brain that may become unbalanced and cause sleep problems (insomnia).
Temazepam is used to treat insomnia symptoms, such as trouble falling or staying asleep.

Temazepam may also be used for other purposes not listed in this medication guide.

Important information about temazepam
Temazepam may cause a severe allergic reaction. Stop taking temazepam and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Take this medication only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine.

Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking temazepam and talk with your doctor about another treatment for your sleep disorder.

Do not use this medication if you are allergic to temazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or triazolam (Halcion). This medication can cause birth defects in an unborn baby, or withdrawal symptoms in a newborn. Do not use temazepam if you are pregnant.

Before taking temazepam, tell your doctor if you have any breathing problems, glaucoma, kidney or liver disease, myasthenia gravis, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking temazepam. It can increase some of the side effects, and could possibly cause a fatal overdose.

Avoid using other medicines that make you sleepy. They can add to sleepiness caused by temazepam.

Temazepam may be habit-forming and should be used only by the person it was prescribed for. This medicine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Before taking temazepam:
Some people using temazepam have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking temazepam and talk with your doctor about another treatment for your sleep disorder.

Do not use this medication if you are allergic to temazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or triazolam (Halcion).

Before taking this medicine, tell your doctor if you are allergic to any drugs, or if you have:

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

glaucoma;

kidney or liver disease;

myasthenia gravis;

a history of depression or suicidal thoughts or behavior; or

a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take temazepam.

Temazepam can cause birth defects in an unborn baby. It may also cause addiction or withdrawal symptoms in a newborn if the mother takes temazepam late in pregnancy. Do not use this medicine if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Temazepam may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of this medicine may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking temazepam.

Do not give this medication to anyone under 18 years old.

How should I take temazepam?
Take temazepam exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take temazepam only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine. Contact your doctor if this medicine seems to stop working as well in helping you fall asleep and stay asleep. Temazepam should be used for only a short time to treat insomnia. After 7 to 10 nights of use, talk with your doctor about whether or not you should keep taking temazepam.

Your insomnia symptoms may return when you stop using temazepam after using it over a long period of time. You may need to use less and less before you stop the medication completely.

Temazepam may be habit-forming and should be used only by the person it was prescribed for. Temazepam should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Store temazepam at room temperature away from moisture and heat.

Keep track of how many tablets have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

See also: Temazepam dosage (in more detail)

What happens if I miss a dose?
Since temazepam is taken as needed, you are not likely to be on a dosing schedule. Take temazepam only when you have time for several hours of sleep.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of temazepam can be fatal, especially if taken with alcohol.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, slurred speech, tremors, a slow heartbeat, shallow breathing, feeling light-headed, fainting, seizure (black-out or convulsions), and coma.

What should I avoid while taking temazepam?
Do not drink alcohol while you are taking temazepam. It can increase some of the side effects, and could possibly cause a fatal overdose. Temazepam can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Temazepam side effects:
Temazepam may cause a severe allergic reaction. Stop taking temazepam and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using temazepam and call your doctor at once if you have any of these serious side effects:

weak or shallow breathing;

fast or pounding heartbeats;

confusion, slurred speech, unusual thoughts or behavior;

hallucinations, agitation, aggression;

thoughts of suicide or hurting yourself;

restless muscle movements in your eyes, tongue, jaw, or neck;

pale skin, easy bruising or bleeding, unusual weakness;

fever, chills, body aches, flu symptoms;

problems with urination; or

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

daytime drowsiness (or during hours when you are not normally sleeping);

amnesia or forgetfulness;

muscle weakness, lack of balance or coordination;

numbness, burning, pain, or tingly feeling;

headache, blurred vision, depressed mood;

feeling nervous, excited, or irritable;

nausea, vomiting, stomach discomfort; or

dry mouth, increased thirst.

Saturday 28 November 2015

Bonavar 2.5mg by Body Research

Bonavar 2.5mg by Body Research


Product Description
Bonavar - 50 tabs of 2.5mg per tab:

BODY RESEARCH (Thailand):

Oxandrolone is one of the very few steroids that does not aromatize into estrogen, at any dosage, which has various advantages for the athlete.

Common uses and directions for Bonavar / Anavar, oxandrolone Oxandrolone has often been used as a growth-promoting agent in the therapy of boys with growth delays in adolescence. Oxandrolone is also used in treating girls affected with Turner's syndrome, another growth-delay ailment.

In obese individuals, oral oxandrolone has been shown to decrease subcutaneous abdominal fat more than Testosterone enanthate or weight loss alone, and it also tended to produce favorable changes in visceral fat.

Bonavar / Anavar, oxandrolone, tablets. Each Bonavar / Anavar tablet contains 2.5 mg. oxandrolone. Bonavar / Anavar, brand name Bonavar, comes in packs of 50 tablets and is manufactured by Body Research Ltd., Thailand.

Common uses and directions for Bonavar / Anavar, oxandrolone

Oxandrolone has often been used as a growth-promoting agent in the therapy of boys with growth delays in adolescence. Oxandrolone is also used in treating girls affected with Turner's syndrome, another growth-delay ailment. In obese individuals, oral oxandrolone has been shown to decrease subcutaneous abdominal fat more than Testosterone enanthate or weight loss alone, and it also tended to produce favorable changes in visceral fat.
Athletes like oxandrolone for three reasons. First, oxandrolone causes a strong strength gain by stimulating the phosphocreatine synthesis in the muscle cell without depositing water in the joints and the muscles.

Secondly, oxandrolone is one of the very few steroids that does not aromatize into estrogen, at any dosage, which has various advantages for the athlete.

The third reason for the popularity of Bonavar / Anavar is that oxandrolone does not influence the body's own testosterone production.

A suitable dosage of Bonavar / Anavar for a male athlete is 0.125 mg./pound of body weight per day. Women should not take more than about half of that dosage, though. Bonavar / Anavar is normally taken two to three times daily after meals thus assuring an optimal absorption of the oxandrolone.

Friday 27 November 2015

Dronabol DS 10mg by Bangkok Lab

Dronabol DS 10mg by Bangkok Lab



Product Description
Generic Name:

methandrostenolone/Methandienone

Dianabol/Dronabol has always been one of the most popular anabolic steroids available. Dianabol's/Dronabol's popularity stems from it's almost immediate and very strong anabolic effects. 4-5 tablets a day is enough to give almost anybody dramatic results. It is usually stacked with deca durabolin and testosterone enanthate. Along with strong anabolic effects comes the usual androgen side effects, users often report an overall sense of well being. Dianabol/Dronabol is a strong anabolic and androgenic product. It most often produced dramatic gains in size and strength. Dianabol was also shown to increase endurance and glycogen retention.

The down side is that this drug is responsible for a number of side effects. It is an alpha alkylated 17 compound, which is quite toxic to the liver. Regarded by many athletes as being one of the most effective oral steroids ever produced.Dianabol is still one of the most effective strength and size building oral steroids probably second only to Anadrol 50 but it is not as harsh on the system as Anadrol 50 is.

Contrary to what many would expect, this compound is actually only a weak agonist of the androgen receptor with poor binding. It follows, then, that its value must mostly come from non-AR-mediated effects. It is therefore a Class II steroid. Since it is not very effective in activating ARs, it should be stacked with a Class I steroid that is effective in this regard, such as Primobolan , Deca Durabolin , or trenbolone acetate . There is no point in stacking it with Anadrol, which has similar activity -- one ought to simply use the more appropriate drug. With testosterone or Deca, Dianabol is to be preferred with Primobolan or trenbolone acetate, Anadrol is to be preferred (though Dianabol is still a good choice) because Anadrol does not aromatize.

Methandrostenolone converts to estradiol via aromatase. The amount of this conversion may be reduced by use of Arimidex , or less preferably Cytadre. Or if the conversion is allowed, Clomid may be used to block adverse estrogenic effects.

Syringes 5ml x100 Piece

Syringes 5ml x100 Piece



Product Description
A syringe is a simple pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube (called a barrel), allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle, or tubing to help direct the flow into and out of the barrel. Syringes are often used to administer injections, insert intravenous drugs into the bloodstream, apply compounds such as glue or lubricant, and measure liquids.

Black Cobra 125mg

Product Description
Generic Name:
Sildenafil Citrate
Kobra works by increasing the effects of nitric oxide (NO), a substance that serves many key functions in biological processes throughout the body. One of the most well known and important functions of NO is the dilation of blood vessels. This allows greater blood flow to the muscles, which of course can be valuable to an athlete during competition.



What is more interesting to me is the role of NO on muscles during resistance training. JE Anderson found that NO appears to be a vital signal in the activation of muscle satellite cells in response to damage. Satellite cell activation is the key first step in the repair and hypertrophy of muscle cells after heavy training. It may therefore enhance the hypertrophy response to exercise, working at the most basic and primary level of the process.

In addition to this, there is evidence that suggests that Viagra may work to amplify the "pump" response during training. The pump is thought to happen when contracting muscle fibers signal local vascular relaxation (increasing the blood flow to the working muscles). According to KS Lau and coworkers, NO generated by neuronal NO synthase in contracting skeletal muscle fibers may regulate vascular relaxation via a cGMP-mediated pathway. Since the mechanism of action for Viagra is amplification of the cGMP pathway, there is ample reason to believe that the drug may indeed affect the blood flow and pump to the muscle, and therefore indirectly aid in the hypertrophy response.

Common uses and directions for Sildenafil Citrate:

Normally nerves or blood vessels in men with male erectile dysfunction do not work properly, which prevents them from achieving an erection. It works to restore the blood flow to the penis making it easier to achieve and sustain longer erections.
  It increases the blood flow to the penis by helping the arteries in the penis relax and expand. As the arteries in the penis expand and harden, veins that normally carry away blood flow to the penis are compressed resulting in an erection.
  It takes at least 30 minutes before it starts to work, and remains active for up to 4 hours. The erection goes away after intercourse.
Men who are currently using medicines that contain nitrates, such as nitroglycerin should not use it because taken together they can lower the blood pressure too much. Kobra should not be used by women or children.

Sildenafil Citrate additional information:
Common uses:

  is used to treat erection difficulties, such as erectile dysfunction (ED).

Directions:

  comes as a tablet containing 150 mg. sildenafil citrate, to take by mouth.
For most men, the recommended dose is 50 mg. taken, as needed, approximately 1 hour before sexual activity. However, sildenafil citrate may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.

Precautions:

A starting dose of 25 mg. should be considered individuals of the age 65+ and in individuals with hepatic impairment or severe renal impairment.
Given the extent of the interaction with patients receiving concomitant therapy with ritonavir, it is recommended not to exceed a maximum single dose of 25 mg. of Viagra in any 48 hour period.
Sildenafil citrate potentiates the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors or nitrates in any form is therefore contraindicated.
Treatments for erectile dysfunction, including Kobra/Viagra, should not be generally used in men for whom sexual activity is inadvisable because of their underlying cardiovascular status.
Patients who have suffered a myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months, patients with resting hypotension or hypertension, patients with cardiac failure or coronary artery disease and patients with retinitis pigmentosa should use Kobra/Viagra with great caution.
The safety of Viagra is unknown in patients with bleeding disorders and patients with active peptic ulceration.
Kobra/Viagra should be used with caution by individuals with anatomical deformation of the penis and by individuals who have conditions which may predispose them to priapism.
The safety and efficacy of combinations of Viagra with other treatments for erectile dysfunction have not been studied. Therefore, the use of such combinations is not recommended.

Possible side effects:

The most frequently observed side effects of Kobra/Viagra includes headache, flushing, dyspepsia and nasal congestion.
Less frequent side effects include erections that will not go away and vision changes. In the event that an erection persists longer than 4 hours, seek immediate medical assistance. Other less frequent side effects include urinary tract infection, abnormal vision, diarrhea, dizziness and rash.
If you notice other effects not listed above, contact your doctor.

Overdose:

If overdose of Kobra/Viagra is suspected, contact your local poison control center or emergency room immediately.

Additional information:

Keep Viagra/Kobra in a tightly closed container and out of reach of children. Store  at room temperature and away from excess heat and moisture (not in the bathroom).

Thursday 26 November 2015

Syringes 3ml x 100 Piece

Syringes 3ml x 100 Piece
Product Description
A syringe is a simple pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube (called a barrel), allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle, or tubing to help direct the flow into and out of the barrel. Syringes are often used to administer injections, insert intravenous drugs into the bloodstream, apply compounds such as glue or lubricant, and measure liquids.

Cobra 150mg

Product Description
Generic Name:
Sildenafil Citrate
Kobra works by increasing the effects of nitric oxide (NO), a substance that serves many key functions in biological processes throughout the body. One of the most well known and important functions of NO is the dilation of blood vessels. This allows greater blood flow to the muscles, which of course can be valuable to an athlete during competition.



What is more interesting to me is the role of NO on muscles during resistance training. JE Anderson found that NO appears to be a vital signal in the activation of muscle satellite cells in response to damage. Satellite cell activation is the key first step in the repair and hypertrophy of muscle cells after heavy training. It may therefore enhance the hypertrophy response to exercise, working at the most basic and primary level of the process.

In addition to this, there is evidence that suggests that Viagra may work to amplify the "pump" response during training. The pump is thought to happen when contracting muscle fibers signal local vascular relaxation (increasing the blood flow to the working muscles). According to KS Lau and coworkers, NO generated by neuronal NO synthase in contracting skeletal muscle fibers may regulate vascular relaxation via a cGMP-mediated pathway. Since the mechanism of action for Viagra is amplification of the cGMP pathway, there is ample reason to believe that the drug may indeed affect the blood flow and pump to the muscle, and therefore indirectly aid in the hypertrophy response.

Common uses and directions for Sildenafil Citrate

Normally nerves or blood vessels in men with male erectile dysfunction do not work properly, which prevents them from achieving an erection. It works to restore the blood flow to the penis making it easier to achieve and sustain longer erections.
  It increases the blood flow to the penis by helping the arteries in the penis relax and expand. As the arteries in the penis expand and harden, veins that normally carry away blood flow to the penis are compressed resulting in an erection.
  It takes at least 30 minutes before it starts to work, and remains active for up to 4 hours. The erection goes away after intercourse.
Men who are currently using medicines that contain nitrates, such as nitroglycerin should not use it because taken together they can lower the blood pressure too much. Kobra should not be used by women or children.

Sildenafil Citrate additional information:
Common uses:

  is used to treat erection difficulties, such as erectile dysfunction (ED).

Directions:

  comes as a tablet containing 150 mg. sildenafil citrate, to take by mouth.
For most men, the recommended dose is 50 mg. taken, as needed, approximately 1 hour before sexual activity. However, sildenafil citrate may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.

Precautions:

A starting dose of 25 mg. should be considered individuals of the age 65+ and in individuals with hepatic impairment or severe renal impairment.
Given the extent of the interaction with patients receiving concomitant therapy with ritonavir, it is recommended not to exceed a maximum single dose of 25 mg. of Viagra in any 48 hour period.
Sildenafil citrate potentiates the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors or nitrates in any form is therefore contraindicated.
Treatments for erectile dysfunction, including Kobra/Viagra, should not be generally used in men for whom sexual activity is inadvisable because of their underlying cardiovascular status.
Patients who have suffered a myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months, patients with resting hypotension or hypertension, patients with cardiac failure or coronary artery disease and patients with retinitis pigmentosa should use Kobra/Viagra with great caution.
The safety of Viagra is unknown in patients with bleeding disorders and patients with active peptic ulceration.
Kobra/Viagra should be used with caution by individuals with anatomical deformation of the penis and by individuals who have conditions which may predispose them to priapism.
The safety and efficacy of combinations of Viagra with other treatments for erectile dysfunction have not been studied. Therefore, the use of such combinations is not recommended.

Possible side effects:

The most frequently observed side effects of Kobra/Viagra includes headache, flushing, dyspepsia and nasal congestion.
Less frequent side effects include erections that will not go away and vision changes. In the event that an erection persists longer than 4 hours, seek immediate medical assistance. Other less frequent side effects include urinary tract infection, abnormal vision, diarrhea, dizziness and rash.
If you notice other effects not listed above, contact your doctor.

Overdose:

If overdose of Kobra/Viagra is suspected, contact your local poison control center or emergency room immediately.

Cipram 20mg by Landbeck

Cipram 20mg by Landbeck



Product Description
Citalopram 20mg tablets when used in Anxiety:
Citalopram hydrobromide (Sit-al-oh-pram hi-droh-broh-mide) is a medicine which is used in depression and panic disorder.

The information in this Medicine Guide for citalopram hydrobromide varies according to the condition being treated and the particular preparation used.

Your medicine:
Citalopram hydrobromide is used to treat a variety of mental health problems. It is thought that Citalopram hydrobromide increases the activity and levels of certain chemicals in the brain. This can improve symptoms such as depression and anxiety.

Some people who take Citalopram hydrobromide may find that it intensifies depression and suicidal feelings in the early stages of treatment. These people have an increased risk of self-harm or suicide in the early stages of taking Citalopram hydrobromide. As Citalopram hydrobromide starts to work these risks decrease.

If you are taking Citalopram hydrobromide, or you care for someone who is taking Citalopram hydrobromide, you need to look out for changes in thoughts or behaviour that could be linked to self-harm or suicide.

If you notice any of these changes or are worried about how Citalopram hydrobromide is affecting you or someone you care for, you should contact your prescriber, a mental health professional or NHS Direct as soon as possible.

It is important that you discuss with your prescriber how long it will take before you can expect to feel any benefits from taking Citalopram hydrobromide.

Other information about Citalopram hydrobromide:

your doctor may start you on a low dose of this medicine and then increase the dose depending on how you respond to treatment
Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you:
Citalopram hydrobromide is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

are aged over 65 years
are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
are having electroconvulsive therapy
are taking monoamine oxidase inhibitors or have taken them within the last two weeks
have diabetes
have epilepsy
have had bleeding problems
have had glaucoma
have kidney problems
have liver problems
have metabolic problems
have narrow angle glaucoma
have or have had mania
have or have had thoughts of committing suicide
have psychosis
have recently had a heart attack
have, have had or have risk factors for developing heart problems
Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for someone under 18 years of age.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

to check that this medicine is not having any undesired effects
to determine whether or not the medicine is suitable and whether it must be prescribed with extra care
Over time it is possible that Citalopram hydrobromide can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Citalopram hydrobromide has become unsuitable, it is important that the prescriber is contacted immediately.

Alcohol:
Alcohol can interact with certain medicines.

It is best to avoid drinking alcohol while you are taking this medicine.

Diet:
Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Citalopram hydrobromide:

there are no specific foods that you must exclude from your diet when taking Citalopram hydrobromide
Driving and operating machinery:
When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Citalopram hydrobromide:

this medicine could affect your ability to drive or operate machinery
You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy:
Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Citalopram hydrobromide:

you should only take this medicine during pregnancy if your doctor thinks that you need it
children born to mothers who took Citalopram hydrobromide during the late stages of pregnancy may need regular check-ups
You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Citalopram hydrobromide, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

Breast-feeding:
Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Citalopram hydrobromide:

women who are taking Citalopram hydrobromide should not breast-feed
Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

Oxy 80mg (OC 80)

OC 80 (Oxycontin 80 mg):
Generic Name:
oxycodone



Pill imprint OC 80 has been identified as Oxycontin 80 mg.

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics. FDA has not classified the drug for risk during pregnancy. OxyContin 80 mg has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.

Wednesday 25 November 2015

T3 Cytomel 20mcg by LA Pharma

T3 Cytomel 20mcg by LA Pharma



Product Description
Cytomel (liothyronine sodium)
Cytomel is a synthetic T3 hormone. As you may already know, most natural T3 is not produced directly by your thyroid gland, but rather is converted from the T4 thyroid hormone.

Cytomel T3 Weight Loss:
Natural T3 is a regulator of the oxidative metabolism of energy producing substrates (food or stored substrates like fat, muscle, and glycogen) by the mitochondria. The mitochondria, as you will recall from your high school biology class, are usually referred to as the "cells powerhouses" because they produce ATP. Taking Cytomel (supplemental T3) greatly increases the uptake of nutrients into the mitochondria and also their oxidation rate (i.e. the rate at which they are burned for energy), by increasing the activities of the enzymes involved in the oxidative metabolic pathway. Everything is working harder, in other words, and more fuel is needed to supplement this increased work rate. Therefore, as you can guess, taking supplemental Cytomel will increase your bodys energy demands. And if you are in a hypocaloric state, you will begin burning even fatter primarily due to an increase in ATP. This increased ATP causes an increase in overall metabolic activity. This is exactly what we want, and is why we would be taking thyroid hormones like Cytomel in the first place. If you arent taking anabolic steroids with your Cytomel, however, your body may start to eat away muscle to provide energy for you to function. Remember mitochondria/ATP arent very picky, but they are very efficient. What I mean by this is that they will use whatever is on hand to generate energy for your body to continue functioning, fat, protein, glucose; it doesnt matter to ATP, as long as theres something to give them energy. Taking this drug will increase their need to find something to burn to create this energy. Ergo, if we arent taking anabolic steroids while taking our T3, we may lose too much muscle, especially while dieting.

Thus we can see that there are many advantages to using Cytomel to optimize our metabolic rate. It will also increase your bodys ability to synthesize protein, but from what Ive seen personally, it acts as a catabolic when it isnt administered with anabolic steroids. It is often the last thing added into a precontest diet, as it has a reputation for getting rid of the last few percentages of bodyfat& the "sticky fat" as its called in bodybuilding, the fat that just doesnt want to leave you in the last few weeks of dieting. I think this is a poor use for this drug, and that it should be the first thing added into a diet to lose fat, as it will optimize your metabolic rate, which should be done at the outset of a diet, not after the calorie restriction has diminished your thyroid output and you are adding it in simply to replace what was lost.

Cytomel Side Effects:
Unfortunately, in all of the studies Ive seen, T3 also increased growth hormone production.  As we all know, GH is also a strongly lipolytic compound, and this is another mechanism by which T3 may exert its effects, although I suspect this would only be a small percentage of its overall effects. This being the case, it has always been somewhat problematic to me to note that when GH and T3 are used together, the increased nitrogen retention normally found with GH use is negated. . If you were only using T3 and GH this may be a problem, but as Ive already stated, you are going to need some anabolic agents if you are using T3. And as you have read previously, I recommend the veritable anabolic/lipolytic orgy of Insulin, T3, Anabolic Steroids, GH, and insulin, for 100% maximum results in minimal time.On the brighter side, and of special note to dieters, administration of T3 has been shown to upregulate the beta 2 receptors in fat tissue. As you know clenbuterol and similar compounds downregulate this receptor, so using T3 with your clen will help stave off or reverse this downregulation. I would still recommend taking your benadryl every third week, though.

Going off Cytomel:
Finally, I would like to address the issue of recovery of your natural thyroid function after you stop taking cytomel. The horror stories of people on permanent thyroid replacement just arent true. I remember a few years ago, the rumor was circulating that the current Ms.Fitness had permanently shut off her thyroid gland, and was now fat and on thyroid hormone permanently. This is just another horror story based in nothing but conjecture and rumor, the studies Ive looked at have shown people recovering their thyroid hormone relatively quickly (within months, at most) after going off of several YEARS (!) of thyroid replacement therapy (10)(11). I speculate that you can optimize your metabolic rate with Cytomel for 9-10 months a year, and just normalize yourself for 2-3 months (perhaps the winter, when you are mostly covered up), and then go right back on. Some people in the studies I read were on T3 for 30 years and recovered their natural thyroid function within short order. I think we can safely spend an athletic career using Cytomel 9-10 months out of the year, and just taking those few months off to normalize ourselves. Is this aggressive? Yes. Is this unsafe? NO.

Testosterone Enanthate 250mg Irani

Product Description
Testosterone Enanthate



Testosterone Enanthate a long acting form of the parent hormone testosterone. In this particular case, the parent hormone has been attached to the Enanthate ester to delay its release into the bloodstream over several days.

Testosterone belongs to the class of medications called androgens (male hormones). This medication is used to replace testosterone in men who have conditions caused by low testosterone levels, such as erectile dysfunction (difficulty getting or keeping an erection). There are other possible causes for erectile dysfunction, so testosterone is only used to treat erectile dysfunction that is caused by low testosterone

Testosterone Enanthate is probably the most commonly used form of testosterone by both athletes and bodybuilders alike. Further, in the United States, it is one of the most commonly prescribed testosterone compounds for the treatment of low testosterone or andropause conditions; however, Testosterone Cypionate is the most commonly prescribed when an injectable form is offered. Extremely effective for building muscle and enhancing strength, Testosterone Enanthate can also help with losing fat and it comes with some great news; its very cheap and widely available.

This medication works by replacing the testosterone that the body is missing. Testosterone enanthate should only be used if testosterone deficiency has been confirmed by symptoms and blood tests.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

In-order to understand exactly how Testosterone Enanthate (commonly referred to as "test-e") builds muscle and burns fat, first well take a look at androgens and what they do in the body. You see, hormones are substances secreted by one cell that has an effect on the functions of another cell. Testosterone is manufactured in the Leydigs cells of the testes (in men) and the adult male produces between 2.5 and 11mgs of Test per day.

Testosterone induces changes in shape, size and also can change the appearance and the number of muscle fibers(7). Androgens like testosterone, which is exactly what Testosterone Enanthate is can protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones(8), thus inhibiting their ability to send a message to muscle cells to release stored protein. Remember, testosterone sends a message to muscle cells to store more contractile protein (called actin and myosin); glucocorticoid hormones send the opposite message. In addition, Testosterone Enanthate has the ability to increase erythropoiesis (red blood cell production) in your kidneys(9), and a higher Red Blood Cell (RBC) count will improve endurance via better oxygenated blood. More RBCs can also improve recovery from strenuous physical activity. Of course, aggression levels can rise dramatically with the use of exogenous testosterone (15); however, its important to remember aggression in of itself is not a bad thing; what we do with it is what makes it right or wrong. At any rate, Testosterone Enanthate holds no mind altering traits or nature whatsoever.

All of these great benefits are to be had with the use of Testosterone Enanthate alone, but realistically, it will in most cases be part of a cycle containing one or more other steroids. People who are bulking will probably choose Deca Durabolin or Trenbolone compounds, and of course the possibility of powerful oral steroids like Anadrol or Dianabol. Then we have those who are cutting, and they will probably steer towards Equipoise and once again Trenbolone, along side compounds such as Anavar, Masteron, Winstrol and perhaps Primobolan; all are solid options. Very often users will administer Testosterone Enanthate once or twice a week, but blood levels are still above baseline with this steroid at around day eight (16).Common wisdom holds that the testosterone portion of any such cycle should be equal to or greater than any other injectable steroids portion (on a mg basis); however, this isnt always needed, but its a good rule of thumb to ensure no low testosterone condition exists.

As you may have suspected, Testosterone Enanthates anabolic/androgenic effects are dose dependent; the higher the dose the higher the muscle building effect.

The dose of testosterone enanthate varies based on age, response to treatment, and side effects. The maximum dose is 400 mg per month. It is given as an injection into the gluteal muscle (buttocks) by a doctor.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important this medication be given exactly as recommended by your doctor. If you miss an appointment to receive testosterone enanthate, contact your doctor as soon as possible to reschedule your appointment.

Testoviron Depot 250mg/1ml by Byer

Testoviron Depot 250mg/1ml by Byer



Product Description

Testoviron 250 is an injectable steroid made by Byer, its active substance is Testosterone Enanthate.
Testosterone Enanthate is probably the most commonly used form of testosterone by both athletes and bodybuilders alike.
Testoviron 250 is an oil based injectable steroid, which is designed to slowly release testosterone from the injection site. This slow release delivery leads to an elevation in testosterone levels lasting for approximately two weeks (it may even take as long as three weeks for the drug levels to fully diminish). Due to its relatively long activity level, Testosterone Enanthate is favored by the medical profession and is primarily used to treat cases of hypogonadism and similar disorders where low androgen levels are at fault. As with all testosterone products it has strong anabolic and androgenic activity. Gains in strength and muscle mass are notable, along with an increase in libido. It has also been noted that a relief in tendon pain and an increase in stamina are direct effects of Testoviron 250 administration. This is probably due to increased water retention coupled with an increase in red blood cells – leading to a greater oxygen uptake in the blood.
Testosterone is a highly anabolic and androgenic hormone, it has an anabolic (muscle building) as well as anabolic rating of 100 each, respectively. Testoviron 250 exerts the majority of its effects by promoting increased nitrogen retention in the muscle. Testoviron 250 is also known to increases levels of the growth factor IGF-1 in both the muscle tissue as well as the liver. This steroid also increases the activity of satellite cells, which are cells that play an active role in repairing exercise-damaged muscle. Testoviron 250 exerts these effects primarily by genomic mechanisms, meaning that it binds to the androgen receptor (AR) thus initiating gene transcription. This stimulation of the AR promotes various of the AR dependant mechanisms for both muscle gain and fat loss, as well as reducing catabolic glucocorticoid hormones, and increasing red blood cell production.

HOW DOES IT WORKS?

Weekly totals of 250-1000mg weekly are frequently used, and sometimes more for the highly advanced athlete. Due to the relatively long half life of Testoviron 250 (4-5 days), injections are usually administered twice per week. This will allow stable blood levels to be maintained. When the level of steroid tapers down, a new injection is made, keeping everything fairly level. This is unlike Sustanon, which requires more frequent injections for the same effect. For a first cycle, 500 mg alone of Testoviron 250, shot two times weekly (Monday and Thursday for example), for 10 weeks along with standard post cycle therapy would be very sufficient for good gains.
As the best mass builder available, Testoviron 250 stacks well virtually everything and can also be used alone with high levels of success. Due to the longer half life of Testoviron 250, a dose of 500 mg per week can be used for the first time user for a period of 10 weeks with very good results. Stacking oral steroids on a first cycle is generally considered uneccessary, because it is impossible to gauge your body's responsiveness to the individual steroids being used and determine which ones cause which side effects. For the more advanced athlete, doses of 500 - 1000 mg of Testoviron 250 are also excellent for creating clear results within a 10 week period. More advanced athletes will often stack Testosterone Enanthate with Dianabol, Deca Durabolin, Primobolan or Equipose to create a powerful mass building stack.
All testosterones aromatize, and enanthate is no exception. The steroid user should be familiar with anti-estrogen compounds such as Nolvadex and Clomid and keep them on hand during cycle in case symptoms of gyno arise. Increases in water weight and fat weight should be expected, and the possibilities of gyno are always out there when using Testoviron 250.
Standard post cycle therapy consisting of either Nolvadex or Clomid should take place after the cycle is over.

SIDE EFFECTS:

Side effects such as water retention usually occur when using Testosterone Enanthate. Gyno, increased rate of hair growth, back acne, increased blood pressure, and aggressiveness, both in the gym and out, are possible when using this steroid. The liver is accustomed to processing testosterone, so liver toxicity is normally not a concern except at extremely high doses.

Tuesday 24 November 2015

Temapezam Eggs 10mg by Generic

Temapezam Eggs 10mg by Generic



Product Description
Temazepam is a short-acting Benzodiazepine. It is normally prescribed to people who have difficulty sleeping, or occasionally to reduce anxiety.

Temazepam is produced as a gel-filled capsule, designed to be taken orally. Temazepam Eggs 30mg Generic is used to treat insomnia symptoms, such as trouble falling or staying asleep temazepam. A normal therapeutic dose of temazepam would be 10mg-30mg. If you have a normal dose of Temazepam you may feel less anxious and start to feel relaxed and sleepy. At higher doses the effects are similar to alcohol - you may feel less inhibited towards other people. Your behaviour may be exaggerated (people who are using Temazepam are often very talkative or over-excited, sometimes even hostile or aggressive) and judgement is impaired. You may have a false sense of confidence, or even believe you are invincible or invisible.

Temazepam is usually prescribed to help people sleep, and the main physical effects of the drug are as a muscle relaxant. The other effects described above are experienced if you take the drug and stay awake.

If you use Benzodiazepines regularly you can become dependant - withdrawal symptoms include anxiety, sleeplessness, panic attacks, loss of appetite, nausea, tremors and sometimes even hallucinations. These symptoms can persist for weeks after stopping use of the drug. Abrupt withdrawal from high doses can cause convulsions and fits, and should never be attempted without medical supervision.

The effects of downers like Temazepam make it more difficult to judge and assess situations than normal. Because of this, if you use the drug you are more vulnerable to accidents (for example when crossing a busy road). You can overdose on Temazepam (causing loss of consciousness), especially if you are using another depressant drug like alcohol or heroin.

If you vomit while you are unconscious, you may choke - avoid using this drug on your own if you can. As with any drug that reduces inhibitions, you may be more likely to have unprotected sex, risking unwanted pregnancy and exposing yourself to sexually transmitted diseases. Temazepam is a drug that should not be injected - the gel in the capsules can resolidify after injection.

Monday 23 November 2015

Ativan 2mg by Wyeth

Product Description
What is Ativan?
Ativan (lorazepam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). It affects chemicals in the brain that may become unbalanced and cause anxiety.



Lorazepam (trademarked as Ativan) is a high-potency, short- to intermediate-acting, 3-hydroxy benzodiazepine drug that has all six intrinsic benzodiazepine effects: anxiolytic, amnesic, sedative/hypnotic, anticonvulsant, antiemetic and muscle relaxant. Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation of hospitalized patients, as well as sedation of aggressive patients.
Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic, as well as adverse, effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. After its introduction in 1977, lorazepam's principal use was in treating anxiety. Among benzodiazepines, lorazepam has a relatively high addictive potential. Lorazepam also has abuse potential; the main types of misuse are for recreational purposes or continued use against medical advice. Its sedative-hypnotic and anterograde amnesia properties are sometimes used for criminal purposes.
Long-term effects of benzodiazepines include tolerance, dependence, a benzodiazepine withdrawal syndrome, and cognitive impairments which may not completely reverse after cessation of treatment; however, for most patients, cognitive impairment is not severe. Withdrawal symptoms can range from anxiety and insomnia to seizures and psychosis. Due to tolerance and dependence, lorazepam is recommended for short-term use, up to two to four weeks only. Adverse effects, including anterograde amnesia, depression and paradoxical effects such as excitement or worsening of seizures, may occur. Children and the elderly are more sensitive to the adverse effects of benzodiazepines. Lorazepam impairs body balance and standing steadiness and is associated with falls and hip fractures in the elderly.
 Medical uses:
Lorazepam has relatively potent anxiolytic effects and its best-known indication is the short-term management of severe anxiety; the FDA advises against use of benzodiazepines such as lorazepam for longer than two to four weeks. It is fast acting, and useful in treating fast onset panic anxiety
Lorazepam has strong sedative/hypnotic effects, and the duration of clinical effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia, in particular in the presence of severe anxiety. It has a fairly short duration of action. Withdrawal symptoms, including rebound insomnia and rebound anxiety, may occur after only seven days' administration of lorazepam.
Lorazepam is sometimes used for individuals receiving mechanical ventilation. However, in critically ill patients, propofol has been found to be superior to lorazepam both in effectiveness and overall cost; as a result, the use of propofol for this indication is now encouraged, whereas the use of lorazepam is discouraged
Its relatively potent amnesic effect, with its anxiolytic and sedative effects, makes lorazepam useful as premedication. It is given before a general anaesthetic to reduce the amount of anaesthetic agent required, or before unpleasant awake procedures, such as in dentistry or endoscopies, to reduce anxiety, to increase compliance, and to induce amnesia for the procedure. Oral lorazepam is given 90 to 120 minutes before procedures, and intravenous lorazepam as late as 10 minutes before procedures. Lorazepam is sometimes used as an alternative to midazolam in palliative sedation. In intensive care units lorazepam is sometimes used to produce anxiolysis, hypnosis, and amnesia.
Intravenous diazepam or lorazepam are first-line treatments for convulsive status epilepticus. Lorazepam is more effective than diazepam in the treatment of status epilepticus. However, phenobarbitol has a superior success rate compared to lorazepam and other drugs, at least in the elderly.
Its marked anticonvulsant properties, and its pharmacokinetic profile, make intravenous lorazepam a reliable agent for terminating acute seizures, but it has relatively prolonged sedation after-effects. Oral lorazepam, and other benzodiazepines, have a role in long-term prophylactic treatment of resistant forms of petit mal epilepsy, but not as first-line therapies, mainly because of the development of tolerance to their effects.
Lorazepam's anticonvulsant and CNS depressant properties are useful for the treatment and prevention of alcohol withdrawal syndrome. In this setting, impaired liver function is not a hazard with lorazepam, since lorazepam does not require oxidation, hepatic or otherwise, for its metabolism.
Lorazepam is sometimes used as an alternative to haloperidol when there is the need for rapid sedation of violent or agitated individuals, but haloperidol plus promethazine is preferred due to better effectiveness and due to lorazepam's adverse effects on respiratory function. However, adverse effects such as behavioural disinhibition may make benzodiazepines inappropriate for some acutely psychotic patients. Acute delirium is sometimes treated with lorazepam, but as it can cause paradoxical effects, it is preferably given together with haloperidol. Lorazepam is absorbed relatively slowly if given intramuscularly, a common route in restraint situations.
Catatonia with inability to speak is responsive and sometimes controlled with a single 2-mg oral, or slow intravenous dose of lorazepam. Symptoms may recur and treatment for some days may be necessary. Catatonia due to abrupt or too rapid withdrawal from benzodiazepines, as part of the benzodiazepine withdrawal syndrome, should also respond to lorazepam treatment. As lorazepam can have paradoxical effects, haloperidol is sometimes given concomitantly.
It is sometimes used in chemotherapy as an adjunct to antiemetics for treating anticipatory nausea and vomiting, i.e. nausea and vomiting caused or worsened by psychological sensitization to the thought of being sick. It is also used as adjunct therapy for cyclic vomiting syndrome.
Lorazepam is also used to treat acute symptoms of vertigo and dizziness for people with Ménière's disease.
Formulation:
Pure lorazepam is an almost white powder that is nearly insoluble in water and oil. In medicinal form, it is mainly available as tablets and a solution for injection, but, in some locations, it is also available as a skin patch, an oral solution, and a sublingual tablet.
Lorazepam tablets and syrups are administered by mouth only. Lorazepam tablets of the Ativan brand also contain lactose, microcrystalline cellulose, polacrilin, magnesium stearate, and colouring agents.
Lorazepam injectable solution is administered either by deep intramuscular injection or by intravenous injection. The injectable solution comes in 1 ml ampoules containing 2 or 4 mg of lorazepam. The solvents used are polyethylene glycol 400 and propylene glycol. As a preservative, the injectable solution contains benzyl alcohol. Toxicity from propylene glycol has been reported in the case of a patient receiving a continuous lorazepam infusion. Intravenous injections should be given slowly and patients closely monitored for side effects, such as respiratory depression, hypotension, or loss of airway control.
Peak effects roughly coincide with peak serum levels, which occur 10 minutes after intravenous injection, up to 60 minutes after intramuscular injection, and 90 to 120 minutes after oral administration, but initial effects will be noted before this. A clinically relevant lorazepam dose will normally be effective for six to 12 hours, making it unsuitable for regular once-daily administration, so it is usually prescribed as two to four daily doses when taken regularly, but this may be extended to five or six, especially in the case of elderly patients who could not handle large doses at once.
Important information about Ativan:
Do not use Ativan if you are allergic to lorazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax). This medication can cause birth defects in an unborn baby. Do not use this medicine if you are pregnant.
Before taking Ativan, tell your doctor if you have any breathing problems, glaucoma, kidney or liver disease, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.
Do not drink alcohol while taking Ativan. This medication can increase the effects of alcohol.
Avoid using other medicines that make you sleepy. They can add to sleepiness caused by lorazepam.
Ativan may be habit-forming and should be used only by the person it was prescribed for. Ativan should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.
Adverse effects:
Any of the five intrinsic benzodiazepine effects possessed by lorazepam (sedative/hypnotic, muscle relaxant, anxiolytic, amnesic, and anticonvulsant) may be considered as adverse or side effects if unwanted. Adverse effects can include sedation and hypotension; the effects of lorazepam are increased in combination with other CNS depressant drugs.Other adverse effects include confusion, ataxia, anterograde amnesia and hangover effects. With long-term use of benzodiazepines, it is unclear whether cognitive impairments fully return to normal after cessation of therapy; cognitive deficits persist for at least six months after withdrawal, but longer than six months may be required for recovery of cognitive function. Lorazepam appears to have more profound adverse effects on memory than other benzodiazepines; it impairs both explicit and implicit memory. In the elderly, falls may occur as a result of benzodiazepines. Adverse effects are more common in the elderly, and they appear at lower doses than in younger patients. Benzodiazepines can cause or worsen depression. Paradoxical effects can also occur, such as worsening of seizures, or paradoxical excitement; paradoxical excitement is more likely to occur in the elderly, children, those with a history of alcohol abuse and in people with a history of aggression or anger problems.Lorazepam's effects are dose-dependent, meaning the higher the dose, the stronger the effects (and side effects) will be. Using the smallest dose needed to achieve desired effects lessens the risk of adverse effects.
Sedation is the side effect for which most patients complain. In a group of around 3500 patients treated for anxiety, the most common side effects complained of from lorazepam were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%). Side effects such as sedation and unsteadiness increased with age.Cognitive impairment, behavioural disinhibition and respiratory depression as well as hypotension may also occur.
Paradoxical effects: In some cases, paradoxical effects can occur with benzodiazepines, such as increased hostility, aggression, angry outbursts, and psychomotor agitation. These effects are seen as more common with lorazepam than other benzodiazepines. Paradoxical effects are more likely to occur with higher doses, in patients with pre-existing personality disorders and those with a psychiatric illness. Frustrating stimuli may trigger such reactions, though the drug may have been prescribed to help the patient cope with such stress and frustration in the first place. As paradoxical effects appear to be dose-related, they usually subside on dose reduction or on complete withdrawal of lorazepam.
Suicidality: Benzodiazepines may sometimes unmask suicidal ideation in depressed patients, possibly through disinhibition or fear reduction. The concern is that, though relatively nontoxic in themselves, benzodiazepines may inadvertently become facilitators of suicidal behaviour.Lorazepam should, therefore, not be prescribed in high doses or as the sole treatment in depression, but only with an appropriate antidepressant.
Amnesic effects: Among benzodiazepines, lorazepam has relatively strong amnesic effects, but patients soon develop tolerance to this with regular use. To avoid amnesia (or excess sedation) being a problem, the initial total daily lorazepam dose should not exceed 2 mg. This also applies to use for night sedation. Five participants in a sleep study were prescribed lorazepam 4 mg at night, and the next evening, three subjects unexpectedly volunteered memory gaps for parts of that day, an effect that subsided completely after two to three days' use.Amnesic effects cannot be estimated from the degree of sedation present, since the two effects are unrelated.
High-dose or prolonged parentally administered lorazepam is sometimes associated with propylene glycol intoxication.
Contraindications:
Lorazepam should be avoided in people with:
Allergy or hypersensitivity – Past hypersensitivity or allergy to lorazepam, to any benzodiazepine, or to any of the ingredients in lorazepam tablets or injections
Severe respiratory failure – Benzodiazepines, including lorazepam, may depress central nervous system respiratory drive and are contraindicated in severe respiratory failure. An example would be the inappropriate use to relieve anxiety associated with acute severe asthma. The anxiolytic effects may also be detrimental to a patient's willingness and ability to fight for breath. However, if mechanical ventilation becomes necessary, lorazepam may be used to facilitate deep sedation.
Acute intoxication – Lorazepam may interact synergistically with the effects of alcohol, narcotics, or other psychoactive substances. It should, therefore, not be administered to a drunk or intoxicated person.
Ataxia – This is a neurological clinical sign, consisting of unsteady and clumsy motion of the limbs and torso, due to failure of gross muscle movement coordination, most evident on standing and walking. It is the classic way in which acute alcohol intoxication may affect a person. Benzodiazepines should not be administered to already-ataxic patients.
Acute narrow-angle glaucoma – Lorazepam has pupil-dilating effects, which may further interfere with the drainage of aqueous humour from the anterior chamber of the eye, thus worsening narrow-angle glaucoma.
Sleep apnea – Sleep apnea may be worsened by lorazepam's central nervous system depressant effects. It may further reduce the patient's ability to protect his or her airway during sleep.
Myasthenia gravis – This condition is characterised by muscle weakness, so a muscle relaxant such as lorazepam may exacerbate symptoms.
Pregnancy and breast feeding – Lorazepam belongs to the Food and Drug Administration (FDA) pregnancy category D, which means it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy. Evidence is inconclusive whether lorazepam, if taken early in pregnancy, results in reduced intelligence, neurodevelopmental problems, physical malformations in cardiac or facial structure, or other malformations in some newborns. Lorazepam given to pregnant women antenatally may cause floppy infant syndrome in the neonate, or respiratory depression necessitating ventilation. Regular lorazepam use during late pregnancy (the third trimester), carries a definite risk of benzodiazepine withdrawal syndrome in the neonate. Neonatal benzodiazepine withdrawal may include hypotonia, reluctance to suck, apneic spells, cyanosis, and impaired metabolic responses to cold stress. Symptoms of floppy infant syndrome and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth. Lorazepam may also inhibit foetal liver bilirubin glucuronidation, leading to neonatal jaundice. Lorazepam is present in breast milk, so caution must be exercised about breast feeding.

Dormicum 7.5mg by Roche

Dormicum 7.5mg by Roche



Product Description
Dormicum/Midazolam:

Dormicum is a short-acting drug in the benzodiazepine class developed by Hoffmann-La Roche in the 1970s. The drug is used for treatment of acute seizures, moderate to severe insomnia, and for inducing sedation and amnesia before medical procedures. It possesses profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties. Midazolam has a fast recovery time and is the most commonly used benzodiazepine as a premedication for sedation; less commonly it is used for induction and maintenance of anesthesia. Flumazenil is a benzodiazepine antagonist drug that can be used to treat an overdose of midazolam as well as to reverse sedation. However, flumazenil can trigger seizures in mixed overdoses and in benzodiazepine dependent individuals so is not used in most cases.

Administration of midazolam by nose or the buccal route (absorption via the gums and cheek) as an alternative to rectally administered diazepam is becoming increasingly popular for the emergency treatment of seizures in children. Midazolam is also used for endoscopy procedural sedation and sedation in intensive care.The anterograde amnesia property of midazolam is useful for premedication before surgery to inhibit unpleasant memories. Midazolam, like many other benzodiazepines, has a rapid onset of action, high effectiveness and low toxicity level. Drawbacks of midazolam include drug interactions, tolerance, withdrawal syndrome as well as adverse events including cognitive impairment and sedation. Paradoxical effects occasionally occur and are most common in children, the elderly,[15] and particularly after intravenous administration

Indications:
Intravenous midazolam is indicated for procedural sedation (often in combination with an opioid, such as fentanyl), for preoperative sedation, for the induction of general anesthesia, and for sedation of ventilated patients in critical care units.Midazolam is superior to diazepam in impairing memory of endoscopy procedures, but propofol has a quicker recovery time and a better memory-impairing effect.It is the most popular benzodiazepine in the intensive care unit (ICU) because of its short elimination half-life, combined with its water solubility and its suitability for continuous infusion. However, for long-term sedation, lorazepam is preferred due to its long duration of action, and propofol has advantages over midazolam when used in the ICU for sedation, such as shorter weaning time and earlier tracheal extubation.There is evidence buccal and intranasal midazolam is easier to administer and more effective than rectally administered diazepam in the emergency control of seizures.In the final stages of end-of-life care, midazolam is routinely used at low doses via subcutaneous injection to alleviate agitation, myoclonus, restlessness or anxiety in the last hours or days of life. At higher doses during the last weeks of life, midazolam is considered a first line agent in palliative continuous deep sedation therapy when it is necessary to alleviate intolerable suffering unresponsive to other treatments,but the need for this is more rare. Midazolam is also sometimes used in neonates who are receiving mechanical ventilation, although morphine is preferred, owing to its better safety profile for this indication.

Oral midazolam is indicated for the short term treatment of moderately severe insomnia in patients who have not reacted adequately to other hypnotics, and who have persistent trouble in falling asleep. Because of midazolam's extremely short duration, it is not used for patients who have trouble staying asleep through the night; moderate to long acting benzodiazepines, such as temazepam, nitrazepam, flunitrazepam and lormetazepam, are used for those purposes. Like other benzodiazepines, midazolam produces a decrease in delta activity, though the effect of benzodiazepines on delta may not be mediated via benzodiazepine receptors. Delta activity is an indicator of depth of sleep within non-REM sleep; it is thought to reflect sleep quality, with lower levels of delta sleep reflecting poorer sleep. Thus, midazolam and other benzodiazepines cause a deterioration in sleep quality. Cyproheptadine may be superior to nitrazepam in the treatment of insomnia, as it enhances sleep quality based on EEG studies.

Midazolam in combination with an antipsychotic drug is indicated for the acute management of schizophrenia when it is associated with aggressive or out of control behaviour. It is also is sometimes used for the acute management of seizures such as status epilepticus. Long-term use for the management of epilepsy is not recommended, however, due to the significant risk of tolerance (which renders midazolam and other benzodiazepines ineffective) and the significant side effect of sedation. A benefit of midazolam is that in children it can be administered buccally or intranasally at home or at school for emergency control of acute seizures, including status epilepticus. Midazolam is effective for refractory status epilepticus, and has advantages of being water soluble, having a rapid onset of action and not causing metabolic acidosis from the propylene glycol vehicle, which occurs with other benzodiazepines. Drawbacks include a high degree of breakthrough seizures—due to the short half-life of midazolam—in over 50 percent of people treated, as well as treatment failure in 14–18 percent of people with refractory status epilepticus. Tolerance develops rapidly to the anticonvulsant effect, and the dose may need to be increased by several times to maintain anticonvulsant therapeutic effects. With prolonged use, tolerance and tachyphylaxis can occur and the elimination half-life may increase, up to days.

Availability:
Dormicum brand midazolam is marketed by Roche as white, oval 7.5 mg tablets in boxes of 2 or 3 blisterstrips of 10 tablets, and as blue, oval 15 mg tablets in boxes of 2 blisterstrips of 10 tablets. The tablets are imprinted with "Roche" on one side and the dose of the tablet on the other side. Dormicum is also available as 1 ml, 3 ml and 10 ml ampoules at a concentration of 5 mg/ml. Another manufacturer, Novell Pharmaceutical Laboratories, makes it available as Miloz in 3 ml and 5 ml ampoules. Midazolam is the only water-soluble benzodiazepine available. Another maker of the product is Roxanne Laboratories in an oral solution Midazolam HCl Syrup, 2mg/mL Clear, red to purplish-red syrup and is cherry in flavor. It becomes soluble when the injectable solution is buffered to a pH of 2.9–3.7. Midazolam is also available in liquid form. Midazolam can be administered intramuscularly, intravenously, intrathecally, intranasally,buccally,or orally.

 Pregnancy:
Midazolam, when taken during the third trimester of pregnancy, may cause severe risk to the neonate, including benzodiazepine withdrawal syndrome with possible symptoms including hypotonia, apnoeic spells, cyanosis, and impaired metabolic responses to cold stress. Symptoms of hypotonia and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth.Other neonatal withdrawal symptoms include hyperexcitability, tremor and gastrointestinal upset (diarrhea or vomiting). Breast feeding by mothers using midazolam is not recommended.

Overdose:
See also:
Benzodiazepine overdose
A midazolam overdose is considered a medical emergency and generally requires the immediate attention of medical personnel. Benzodiazepine overdose in healthy individuals is rarely life threatening; however, the toxicity of benzodiazepines increases when they are combined with other CNS depressants such as alcohol, opioids, or tricyclic antidepressants. The toxicity of benzodiazepine overdose and risk of death is also increased in the elderly and those with obstructive pulmonary disease or when used intravenously. Treatment is supportive; activated charcoal can be used within an hour of the overdose. The antidote for an overdose of midazolam (or any other benzodiazepine) is flumazenil (Anexate).While effective in reversing the effects of benzodiazepines it is not used in most cases as it may trigger seizures in mixed overdoses and benzodiazepine dependent individuals.