Getryl (Glimepiride oral tablet)
Highlights for glimepiride
Glimepiride oral tablet is available as a generic drug and as a brand-name drug. Brand name: Amaryl.
Glimepiride comes as a tablet you take by mouth.
Glimepiride is used to treat type 2 diabetes. It helps control blood sugar when used along with a healthy diet and exercise.
What is glimepiride?
Glimepiride is a prescription drug. It comes as an oral tablet.
Glimepiride is available as the brand-name drug Amaryl and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.
This drug may be used as part of a combination therapy. That means you need to take it with other drugs.
Why it's used
Glimepiride is used to reduce high blood sugar levels in people with type 2 diabetes. It’s used in combination with a healthy diet and exercise.
This medication may be used with insulin or other types of diabetes drugs to help control your high blood sugar.
How it works
Glimepiride belongs to a class of drugs called sulfonylureas. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Glimepiride helps your pancreas to release insulin. Insulin is a chemical that your body makes to move sugar (glucose) from your bloodstream into your cells. Once the sugar enters your cells, they can use it as fuel for your body.
With type 2 diabetes, your body doesn’t make enough insulin, or it can't properly use the insulin that it makes, so the sugar stays in your bloodstream. This causes high blood sugar levels (hyperglycemia).
Glimepiride side effects
Glimepiride oral tablet doesn’t cause drowsiness, but it can cause other side effects.
More common side effects
The more common side effects that can occur with glimepiride include:
low blood sugar (hypoglycemia). Symptoms may include:
trembling or shaking
nervousness or anxiety
irritability
sweating
lightheadedness or dizziness
headache
fast heart rate or palpitations
intense hunger
fatigue or tiredness
headache
nausea
dizziness
weakness
unexplained weight gain
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
severe low blood sugar (less than 35 to 40 mg/dL). Symptoms may include:
mood changes, such as irritability, impatience, anger, stubbornness, or sadness
confusion, including delirium
lightheadedness or dizziness
sleepiness
blurred or impaired vision
tingling or numbness in your lips or tongue
headaches
weakness or fatigue
lack of coordination
nightmares or crying out in your sleep
seizures
unconsciousness
hypersensitivity (allergic) reactions. This drug can cause several types of allergic reactions, including:
anaphylaxis. This is a severe and possibly a life-threatening allergic reaction. Symptoms may include trouble breathing, swelling of your throat or tongue, hives, or difficulty swallowing.
angioedema. This involves swelling of your skin, the layers under your skin, and your mucous membranes (inside your mouth).
Stevens-Johnsons syndrome. This is a rare and serious disorder of your skin and mucous membranes (mouth and nose). It starts with flu-like symptoms and is followed by a painful red rash and blisters.
liver damage. Symptoms may include:
yellowing of your skin and the whites of your eyes (jaundice)
stomach pain and swelling
swelling in your legs and ankles (edema)
itchy skin
dark-colored urine
pale stool or tar-colored stool
constant sleepiness
nausea
vomiting
bruising easily
low blood cell or platelet counts. Symptoms may include infections and bruising or bleeding that doesn’t stop as quickly as normal.
low sodium levels (hyponatremia) and syndrome of inappropriate antidiuretic hormone secretion (SIADH). In SIADH, your body is unable to get rid of excess water by urinating. This leads to lower sodium levels in your blood (hyponatremia), which is dangerous. Symptoms may include:
nausea and vomiting
headache
confusion
loss of energy and fatigue
restlessness and irritability
muscle weakness, spasms, or cramps
seizures
coma
Highlights for glimepiride
Glimepiride oral tablet is available as a generic drug and as a brand-name drug. Brand name: Amaryl.
Glimepiride comes as a tablet you take by mouth.
Glimepiride is used to treat type 2 diabetes. It helps control blood sugar when used along with a healthy diet and exercise.
What is glimepiride?
Glimepiride is a prescription drug. It comes as an oral tablet.
Glimepiride is available as the brand-name drug Amaryl and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.
This drug may be used as part of a combination therapy. That means you need to take it with other drugs.
Why it's used
Glimepiride is used to reduce high blood sugar levels in people with type 2 diabetes. It’s used in combination with a healthy diet and exercise.
This medication may be used with insulin or other types of diabetes drugs to help control your high blood sugar.
How it works
Glimepiride belongs to a class of drugs called sulfonylureas. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Glimepiride helps your pancreas to release insulin. Insulin is a chemical that your body makes to move sugar (glucose) from your bloodstream into your cells. Once the sugar enters your cells, they can use it as fuel for your body.
With type 2 diabetes, your body doesn’t make enough insulin, or it can't properly use the insulin that it makes, so the sugar stays in your bloodstream. This causes high blood sugar levels (hyperglycemia).
Glimepiride side effects
Glimepiride oral tablet doesn’t cause drowsiness, but it can cause other side effects.
More common side effects
The more common side effects that can occur with glimepiride include:
low blood sugar (hypoglycemia). Symptoms may include:
trembling or shaking
nervousness or anxiety
irritability
sweating
lightheadedness or dizziness
headache
fast heart rate or palpitations
intense hunger
fatigue or tiredness
headache
nausea
dizziness
weakness
unexplained weight gain
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
severe low blood sugar (less than 35 to 40 mg/dL). Symptoms may include:
mood changes, such as irritability, impatience, anger, stubbornness, or sadness
confusion, including delirium
lightheadedness or dizziness
sleepiness
blurred or impaired vision
tingling or numbness in your lips or tongue
headaches
weakness or fatigue
lack of coordination
nightmares or crying out in your sleep
seizures
unconsciousness
hypersensitivity (allergic) reactions. This drug can cause several types of allergic reactions, including:
anaphylaxis. This is a severe and possibly a life-threatening allergic reaction. Symptoms may include trouble breathing, swelling of your throat or tongue, hives, or difficulty swallowing.
angioedema. This involves swelling of your skin, the layers under your skin, and your mucous membranes (inside your mouth).
Stevens-Johnsons syndrome. This is a rare and serious disorder of your skin and mucous membranes (mouth and nose). It starts with flu-like symptoms and is followed by a painful red rash and blisters.
liver damage. Symptoms may include:
yellowing of your skin and the whites of your eyes (jaundice)
stomach pain and swelling
swelling in your legs and ankles (edema)
itchy skin
dark-colored urine
pale stool or tar-colored stool
constant sleepiness
nausea
vomiting
bruising easily
low blood cell or platelet counts. Symptoms may include infections and bruising or bleeding that doesn’t stop as quickly as normal.
low sodium levels (hyponatremia) and syndrome of inappropriate antidiuretic hormone secretion (SIADH). In SIADH, your body is unable to get rid of excess water by urinating. This leads to lower sodium levels in your blood (hyponatremia), which is dangerous. Symptoms may include:
nausea and vomiting
headache
confusion
loss of energy and fatigue
restlessness and irritability
muscle weakness, spasms, or cramps
seizures
coma
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