Zinobi 30mg by MBL

Zinobi 30mg

Product Description

Generic Name:
Phenobarbitone

Phenobarbital (INN) is a long-acting barbiturate and the most widely used anticonvulsant worldwide, and the oldest still commonly used. It also has sedative and hypnotic properties, but as with other barbiturates, it has been superseded by the benzodiazepines for these indications. The World Health Organization recommends its use as first-line for partial and generalized tonic–clonic seizures (those formerly known as grand mal) in developing countries. It is a core medicine in the WHO Model List of Essential Medicines, which is a list of minimum medical needs for a basic health care system.In more affluent countries, it is no longer recommended as a first- or second-line choice anticonvulsant for most seizure types, though it is still commonly used to treat neonatal seizures.

Phenobarbital (and phenobarbital sodium) is manufactured and supplied in various forms: in tablets of 15, 30, 60 and 100 mg (though not all are available in all countries: for example, in Australia only the 30-mg tablets are available); in an oral elixir (commonly 3 mg/ml in strength); and in a form for injection (as phenobarbital sodium - usually 200 mg/ml). The injectable form is used principally to control status epilepticus, while the oral forms are used for prophylactic and maintenance therapy. The dose range for epilepsy is 60–320 mg/day; its very long active half-life means for some patients, doses do not have to be taken every day, particularly once the dose has been stabilised over a period of several weeks or months, and seizures are effectively controlled. It is occasionally still used as a sedative/hypnotic in anxious or agitated patients who may be intolerant of or do not have access to benzodiazepines, neuroleptics and other, newer drugs. For this purpose, phenobarbital has a lower dose range - around 30–120 mg/day, but this practice is uncommon in developed countries.

How it should be taken :
It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of depression, pain, breathing problems, suicidal tendencies, shock, drug dependency, alcoholism, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.

* It may cause dizziness, drowsiness, or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It should not be used in children less than 12 years. Side Effects :
Central Nervous system - Agitation, confusion, involuntary movements, incoordination, CNS depression, nightmares, nervousness, mental disturbance, hallucinations, sleeplessness, anxiety, drowsiness, and dizziness and thinking abnormality.
Respiratory - Difficulty in breathing or shortness of breath.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Miscellaneous - Headache, injection site reactions, hypersensitivity reactions, fever, liver damage and anemia.


Other Precautions :
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (25°C).

Warning!
This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.
You should not suddenly stop taking this medicine unless your doctor tells you otherwise, as suddenly stopping treatment is likely to make your seizures return. It may also result in withdrawal symptoms such as difficulty sleeping (insomnia), anxiety, tremor, dizziness, nausea and delirium.
Phenobarbital decreases the blood levels of hormonal contraceptives that contain oestrogen and/or progesterone. This can make these types of contraceptive ineffective, or cause breakthrough bleeding. Women taking phenobarbital who need contraception should be prescribed hormonal contraceptives that contain a total of at least 50 micrograms of ethinylestradiol (oestrogen), or use non-hormonal methods of contraception, such as condoms. It is important for women who could get pregnant to discuss contraception and pregnancy with their doctor before starting treatment with this medicine.
This medicine may rarely cause problems with your blood cells. You should consult your doctor immediately if you experience any of the following symptoms, as these may signs of problems with your blood cells: unexplained bruising or bleeding, purple spots, sore throat, mouth ulcers, high